Lifestyle

How can some people eat so much and not get fat?

english.alarabiya: Scientists have discovered a ‘thinness’ gene that may be the reason why some people can eat and not gain weight, according to new research.

A study published by University of British Columbia (UBC) scientist Dr. Josef Penninger and a team of researchers identified a gene called Anaplastic Lymphoma Kinase (ALK) which they say is “involved in the resistance to weight gain.”

After comparing the genetics and clinical profile of 47,012 “healthy thin, and normal weight individuals aged 20-44,” the international team of researchers discovered there was a mutation in the ALK gene in the thin group.

Only about one percent of the population has this mutated gene that helps them stay thin, according to the study.

“We all know these people, who can eat whatever they want, they don’t exercise, but they just don’t gain weight. They make up around one percent of the population,” Penninger was quoted by UBC News as saying.

“We wanted to understand why,” Penninger added. “Most researchers study obesity and the genetics of obesity. We just turned it around and studied thinness, thereby starting a new field of research.”

UBC News reported that the gene is “known to mutate frequently in several types of cancer and has been identified as a driver of tumor development.”

“Our work reveals that ALK acts in the brain, where it regulates metabolism by integrating and controlling energy expenditure,” lead author Michael Orthofer told UBC News.

Energy expenditure is measured by calculating how many calories an individual burns while performing activities such as breathing, circulating blood, digesting food, or exercising.

The research team ‘deleted’ the ALK gene in both flies and mice which resulted in the animals becoming resistant to ‘diet-induced’ obesity.

“Despite consuming the same diet and having the same activity level, mice without ALK weighed less and had less body fat,” according to UBC News.

Next, the team will try to determine how the gene “balances metabolism to promote thinness.” The researchers will also conduct further tests on “more diverse” humans in order to validate the results.

Penninger said it is a possibility that the researchers could “reduce the function” of the ALK gene to see if individuals stay skinny.

Source: Published by english.alarabiya

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Adewole olatunde samuel
Adewole olatunde samuel
1 month ago

It may work on mice but eating too much food may not determine if u will get fat

Ukwade peace
Ukwade peace
1 month ago

Wow, I haven’t seen a case where by eating too much does not lead to fatness.

Gideon
Gideon
1 month ago

It is going to work because eating too much doesn’t make someone to get fat that isn’t

Suleiman Abdullahi
Suleiman Abdullahi
1 month ago

Good research work

TSOKWA PUNARIMAM
TSOKWA PUNARIMAM
1 month ago

Good work

Daniel Ntichika
Daniel Ntichika
1 month ago

M part of dose few… No mata he much I eat, I dnt get fat

Ayodeji Adeniyi
Ayodeji Adeniyi
1 month ago

Because it’s not in their gene to get fat

Balogun Olamide
Balogun Olamide
1 month ago

Yeah it determines the kind of genes in d body some might not even eat much n dey get fatter and fatty. It might be hereditary also

Suleiman Abdullahi
Suleiman Abdullahi
1 month ago

You chop alone you fat

Oghenekome Sylvester
Oghenekome Sylvester
1 month ago

Interesting! I know someone like that a girl actually, very slim. she eats alot but never get fat.

Felicia Moses
Felicia Moses
1 month ago

Wow o, good research

Sunday Bose
Sunday Bose
1 month ago

Eye opener. I got that. Getting fat I think it’s not by eating though

Dele Braimoh
Dele Braimoh
1 month ago

I guess I am among the 1% with the ALK gene because no matter the quantity of food I eat and sleep it never seem to make me fat. Now its all starting to make sense

Nwawuba Emmanuel Chibueze
Nwawuba Emmanuel Chibueze
1 month ago

Wow, that’s interesting, aside today, i never knew there’s a gene mutation that stops people from getting fat even when they consume too much fatty foods

Omoniyi Israel
Omoniyi Israel
1 month ago

person can eat all the food in this world and still tiny like cane

Adepoju oluwapelumi
Adepoju oluwapelumi
1 month ago

To much food will not work in body

Chetachi Nwabueze
Chetachi Nwabueze
1 month ago

Some people are luckier than others I guess

Lokrit yilchini gomper
Lokrit yilchini gomper
1 month ago

This is amazing…
How do a gene that maintain thinness …

Ajagbe Olufemi
Ajagbe Olufemi
1 month ago

How will they compare mice to human

Ajagu Joseph Samson
Ajagu Joseph Samson
1 month ago

Thanks for the information

JOSEPH VICTOR MOSES
JOSEPH VICTOR MOSES
1 month ago

Actually eating is good everything in this world has a limit so that you can get the balance diet

Olawoore Tesleem
Olawoore Tesleem
1 month ago

Eating of excess food without Nutrtion can cause that.

Fatima Abdullahi
Fatima Abdullahi
1 month ago

I am of off those people that eat much but am very slim and to fat

Uzomacomfort
Uzomacomfort
1 month ago

I just hope this research is true

Omenogor Lucky
Omenogor Lucky
1 month ago

This is really nice.

Esther Areo
Esther Areo
1 month ago

Impossible, too much food make someone fat especially too much or excessive intake of balance diet or body building food

Last edited 1 month ago by Esther Areo
AREO Abiodun
AREO Abiodun
1 month ago

Very interested story, so amazing

Atte
Atte
1 month ago

Great research. If this thinness gene can mutate in various types of cancer and is driver of tumor development, then it’s a disease that needs to be cured.

Johnson Hernandez
Johnson Hernandez
1 month ago

But I think eating much makes someone get fat

ogunjemiyo Akinlami
ogunjemiyo Akinlami
1 month ago

it depends on gene throughly some people are eating very well and they may not get fat likewise me I do eat well well but am not fat .And some people do to eat less food and they will fat

Ndumnwere Chima
Ndumnwere Chima
1 month ago

This is a very brilliant research and a very wonderful information.

Osuji Caleb ikechi
Osuji Caleb ikechi
1 month ago

Wow thanks for the information

Emeghurhie Peter
Emeghurhie Peter
1 month ago

The researcher are right because I have see alot of people who eat alot but they don’t get fat .

Onafuwa Oluwasheyi Oladipo
Onafuwa Oluwasheyi Oladipo
1 month ago

Good and detailed research

Idris yayah
Idris yayah
1 month ago

Waw, this is really interestingly.

Obiezu Emmanuel Onyedikachi
Obiezu Emmanuel Onyedikachi
1 month ago

It depends on the persons body there are some that don’t eat very much but they are getting fat while there are some that eat much and they are not getting fat

Mohammed Nma Madiwu
Mohammed Nma Madiwu
1 month ago

Too much eating is not leading to fat

Chima franklyn
Chima franklyn
1 month ago

That is where I belong in thinness gene

John Orobosa
John Orobosa
1 month ago

Eating toomuch doesn’t really cause weight gain in some people. It’s now more obvious having drafted this analysis.

Olayinka Njoku
Olayinka Njoku
1 month ago

Eating too much food does not make one fat, I think fatness or thinness is hereditary.

Ekigho Grace
Ekigho Grace
1 month ago

Wait,how is that even possible….for me I eat and I get fat easily

ojelabi babatunde
ojelabi babatunde
1 month ago

eating too much may not determine the fatness of some people sometimes…..

Emmanuel Aso otisi
Emmanuel Aso otisi
1 month ago

Eating alot of food especially junks doesn’t means you will get fat it depends on the gene

Matthew chinedu
Matthew chinedu
1 month ago

It depends on the person’s body

Dara Cletus
Dara Cletus
1 month ago

Just what I’ve always thought of….
These genes are absolutely different in every bodies…. The presence of your genes could cause either a weight loss.. Weight gain…. And so on…

Walson okieizibe gift
Walson okieizibe gift
1 month ago

if it’s true that means I can’t get fat. it’s really an amazing discovery

Nelson Joseph
Nelson Joseph
1 month ago

My wife is fat and she eat less than I do

Atijere Happy
Atijere Happy
1 month ago

Some say food some say peace of mind..but none of that worked for me..

Ade Roju
Ade Roju
1 month ago

Good research

Stephen Izebhokhale
Stephen Izebhokhale
1 month ago

This is so insightful, imagine a gene responsible for tumor development also responsible for thinness